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Consent of Independent Registered Public Accounting Firm
We consent to the reference to our firm under the caption "Experts" and to the use of our report dated June 25, 2014 (except for
Note 15, as to which the date is October 6, 2014) included in Amendment No. 1 to the Registration Statement (Form S-1 333-198777) and related Prospectus of Proteon Therapeutics, Inc. for
the registration of shares of its common stock.
Ernst & Young LLP
October 7, 2014